About

The ability to identify the human proteome at the level of single individual can significantly influence our comprehension of Life and our ability to prevent treat most of the existing pathologies. Conventional approaches for characterizing proteins can hardly be applied to single persons, thus hindering the development of personalized approaches.

To solve this problem, ProID will develop the next-generation platforms for sequencing amino-acids along protein chains. The ProID idea relies on nanopore technologies and ultrafast Raman spectroscopy. We will exploit cutting-edge machine learning algorithms and quantum computations to reach extremely high sensitivity up to single molecule level.

Protein IDentification

Work Packages

WP1

Innovative plasmonic nanopores providing single amino-acid optical excitation and sensitivity

WP2

Re-engineered Optical Elements

WP3

SPAD array designed for Raman detection

WP4

Machine Learning, reconstruction of Raman spectra from few photons, amino-acid discrimination

WP5

Multiphysics quantum and classical computations of pore/protein/light interactions (optical, mechanical, thermal)
  • WP1

    Innovative plasmonic nanopores providing single amino-acid optical excitation and sensitivity

  • WP2

    Re-engineered Optical Elements
  • WP3

    SPAD array designed for Raman detection
  • WP4

    Machine Learning, reconstruction of Raman spectra from few photons, amino-acid discrimination
  • WP5

    Multiphysics quantum and classical computations of pore/protein/light interactions (optical, mechanical, thermal)

ProID is a research project funded from the European Union’s Horizon 2020 research and innovation actions (RIA) scheme under grant agreement no. 964363.

© proteineID PROJECT